Skin Care Technology

Symptom Treatment or a True Cellular-Level Solution?

Írta: admin · 2025 October 18.

Collagen-Stimulating Actives at the Forefront of Regenerative Skincare

The skin’s firmness, elasticity, and youthful structure are primarily based on the presence of collagen. However, as we age, the rate of collagen production gradually decreases, leading to skin thinning, sagging, and the appearance of wrinkles. The goal of modern skincare now extends beyond mere hydration: the focus has shifted to activating cellular-level regeneration, especially supporting the skin’s own collagen synthesis.

Actives that promote collagen activation are classified into two main categories: biomimetic and non-biomimetic ingredients. Both support the skin’s natural collagen production in different, yet complementary, ways.

Biomimetic Actives – Intelligent Signals for the Cells

Biomimetic (or bio-inspired) ingredients are targeted molecules that mimic the body’s own substances in their structure and function. These materials “trick” the cells, behaving like the body’s natural signaling molecules, thereby activating fibroblasts and stimulating the skin to produce new collagen fibers. Biomimetics perform a near-cellular reprogramming without causing irritation.

Outstanding Examples, Riman Style:

Rimanoside™ – a fermented, plant-derived biomolecule
Fillerstine™ – a lifting-effect, biomimetic peptide complex
Palmitoyl Pentapeptide-4 – a five-amino-acid signal peptide
Rejuviome-R™ – a synergy of plant exosomes and signal peptides
NMN (Nicotinamide Mononucleotide) – raises cellular NAD+ levels
Adenosine – boosts cellular energy
Madecassoside – a primary triterpene of Centella Asiatica, which, besides its anti-inflammatory and wound-healing effects, stimulates collagen I and III production.
Collageneer® – a patented natural active ingredient

Effective, but Non-Biomimetic Collagen Stimulants

Non-biomimetic actives do not mimic the body’s own molecules, but they effectively contribute to collagen formation through other mechanisms. These can include antioxidant protection, anti-inflammatory action, enzyme inhibition, or deep hydration—all environmental factors essential for optimal cellular function.

Main Non-Biomimetic Actives Found in Riman Formulations:

Asiaticoside – enhances fibroblast activity
Vitamin C derivatives – as a collagen cofactor
Antioxidants: EGCG (green tea polyphenol), Ergothioneine, Carnosine
AHA acids – (e.g., glycolic acid)
Niacinamide (Vitamin B3) – barrier-strengthening
Hydrolyzed Collagen – collagen broken down into smaller peptides
Amino Acids and their derivatives – e.g., glycine, proline, arginine – essential for building collagen chains.
Vitamin B5 (Panthenol) – deep hydrating and barrier-regenerating effects
Hyaluronic Acid – moisture-binding
Jeju Volcanic Lava Water – rich in minerals, it aids cellular regeneration and hydration in an ionic form.

Supporting the skin’s natural collagen production is not based on the “miracle” of a single active ingredient, but on the collaboration of multiple molecules and mechanisms working in synergy. Biomimetic ingredients intelligently activate the skin’s own regenerative processes, while non-biomimetic components create the necessary environment for collagen synthesis to be truly effective. This dual-action, Riman-style approach—the integration of science and nature—is the key to forward-thinking and long-lasting skin rejuvenation.